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Pipette Calibration: Acronyms, Regulations & What They Really Mean

Requirements evolve. Language changes. Standards update. But the foundational concepts behind pipette calibration regulations remain consistent. This guide is designed to educate you on the basics and point you to the appropriate sources for detailed regulatory interpretation, moving from: Science → Competence → Recognition → Regulation → Oversight The goal is to help you understand

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Which Instrument Should I Use?

Instrument Use Cases Pipette: Pipettes are used to transfer small amounts of liquid, usually ranging from 0.1 µL and up to 10,000 µL.  They are the preferred measuring instrument in situations where accuracy and precision are essential. The pipette comes in single and multichannel options. The single channel mechanical pipette is known to be the

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Types of Pipette Tips

Pipette lingo can get confusing. Stay in the know with these different types of pipette tips. Low Retention Low retention tips are for applications requiring high accuracy and reproducibility. They reduce sample retention by 3-5 times when compared to ordinary tips. Good for use with samples that contain detergents. Graduated Tips These tips have scale

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Top 10 Crimes Committed Against Pipettes

How to NOT use a pipette: #1: Not Proactively Replacing Common Parts at Routinely Scheduled Intervals: Pipettes must have common parts replaced routinely. The following pipette parts should be inspected, tested, and replaced proactively in order to maintain good accuracy and precision. #2 Not Storing Pipettes Vertical When Not in Use: Pipettes like to be

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Pipette Parts – Life Span, Life Cycle, and Performance

The life span of pipette parts may vary based on the: Frequency of pipette use, and if used by multiple personnel Types of liquids aspirated and dispensed Storage conditions when not in use Frequency of preventive maintenance and calibration service There are five (5) common pipette parts/components that attribute to ~95% of all performance issues.

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Frequency of Pipette Preventative Maintenance and Calibration

Most major manufacturers recommend pipette preventative maintenance (PM) and calibration service at least every 12 months, based on use. Twelve months is a good starting interval and should include: Printable Calibration LogPrintable Calibration Stickers (for use with Avery 5960 labels)

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The Reality of Electronic Pipette Calibration

Electronic Pipette Calibration: Instead of the traditional pipetting button and manual volume adjustment, electronic pipettes feature a digital interface to adjust volume, and a motorized piston for aspiration/dispensing.  They use either a stepper motor (using a stepper linear actuator) or a DC motor with an encoder. Like mechanical pipettes, most electronic pipette calibration issues are

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Manufacturer-Made Pipette Tips Vs. Others

There are many different standard/universal pipette tips on the market that can be used and interchanged across different manufacturer’s pipettes. However, lower price and universal fit is not always the best logic when selecting tips for your pipettes. Manufacturer-Made Tip Used With That Manufacturer’s Pipette This pair provides the best results. The tips are specifically

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