If you are receiving a “CO2 ERR” message on your Eppendorf Repeater M4, the potential root cause could be:
Combitip Sensor M4, part number: EP 4982811002, has become defective.
Either the white, round sensor(s) are not recognizing the combitip advanced syringes, or the bronze-colored internal sensor strip is damaged. Replacement sensors can be found here.
You may have mixed batches of Eppendorf Combitip-Plus and Combitip-Avanced syringes.
The M4 repeater is designed to be used with the Combitip-Advanced syringes. If an older style syringe, like the Combitip-Plus, is inserted onto the unit, the Combitip M4 sensor will not recognize it, thus triggering an CO2 ERR/CO3 ERR. The pictures below show the difference.
Eppendorf Combitip-Advanced:
Eppendorf Combitip-Plus (most look like this, with some minor differences in appearance):
The syringe ejector tabs are misaligned, thus preventing the syringe from being loaded and aligned properly with the combitip sensor.
The ejector tabs are charcoal colored/black and “C” shaped on the left and right side of the combitip sensor. It would be relatively easy to notice if the syringe is not loaded fully vertically and looks slanted or misaligned when loaded.
Of course, without seeing the unit, it is more difficult to 100% diagnose the exact cause of the Repeater M4 CO2 ERR. If the unit is confirmed under warranty, consider reaching out to Eppendorf for assistance.
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